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Addictive drugs are substances t hat can lead to substance use disorder, a chronic condition characterized by the inability to stop using the substance despite its harmful effects. These substances target the brain's reward center, releasing feel-good chemicals like dopamine, which can lead to physical dependence and addiction. Most Addictive Substances - *1. Heroin*: A highly addictive opioid with a mean dependence score of 3.00. Heroin use can lead to tolerance, withdrawal symptoms, and severe health problems. - *2. Cocaine*: A stimulant with a dependence score of 2.39. Cocaine use can cause cardiovascular complications, psychiatric disorders, and addiction. - *3. Tobacco/Nicotine*: A highly addictive substance with a dependence score of 2.21. Nicotine use is linked to smoking-related illnesses and deaths. - *4. Methadone*: A synthetic opioid used to treat opioid addiction, but it can be addictive itself. Methadone has a dependence score of 2.08. - *5. Barbiturates*: A class of depressants with a dependence score of 2.01. Barbiturate use can lead to physical dependence, withdrawal symptoms, and overdose. Other Addictive Substances - *Amphetamines*: Stimulants that can cause physical dependence, withdrawal symptoms, and addiction. - *Benzodiazepines*: Anti-anxiety medications that can lead to physical dependence and addiction. - *Methamphetamine/Crystal Meth*: Highly addictive stimulants that can cause severe physical and mental health problems. - *Prescription Opioids*: Medications used to treat pain, but they can be addictive and lead to substance use disorder. - *Cannabis*: A substance that can lead to physical dependence and addiction, particularly in heavy users ¹ ². Signs of Addiction - Loss of control over substance use - Withdrawal symptoms when trying to stop or reduce use - Neglecting responsibilities and activities due to substance use - Continuing to use despite physical or mental health problems - Spending large amounts of time obtaining or using substances Getting Help If you or someone you know is struggling with addiction, it's essential to seek professional help. Treatment options include counseling, medication-assisted therapy, and support groups ³.

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